Publications co-authored by Anagnostec staff members in press
Since the foundation of AnagnosTec, the company has been involved in numerous scientific projects. Expertise in mass spectral analysis in many fields of research is reflected in numerous publication to which AnagnosTec's staff members have contributed. The publication cover issues such as natural product research, cyanobacterial toxins, environmental microbiology, and mass spectral identification of micro-organisms.
In press
Clermont,D., Diard,S., Motreff,L., Vivier,C., Bimet,F., Bouchier,C., Welker,M., Kallow,W., and Bizet,C. Description of Microbacterium binotii sp. nov., isolated from human blood. Int.J.Syst.Evol.Microbiol. online first
Kallow,W., Erhard,M., Shah,H.N., Raptakis,E., and Welker,M. MALDI-TOF MS and microbial identification: years of experimental development to an established protocol . In: Shah, H. N., Gharbia, S. E., and Encheva, V. (Eds.) Mass spectrometry for microbial proteomics. John Wiley & Sons, Chichester, UK. in press.
Shah,H.N., Jacinto,R.C., Ahmod,N., Langham,S., Gharbia,S.E., Kallow,W., and Welker,M. The genus Bacteroides. In: Encyclopedia of Life Sciences. John Wiley & Sons, Chichester, UK. in press
Tonk,L., Welker,M., Huisman,J., and Visser,P.M. Production of cyanopeptolins, anabaenopeptins and microcystins by the harmful cyanobacteria Anabaena 90 and Microcystis PCC 7806. Harmful Algae online first
Dieckmann, R., Helmuth, R., Erhard, M., Malorny, B. Rapid classification/identification of salmonellae at the species and subspecies level using whole-cell MALDI-TOF mass spectrometry. Appl.Environ.Microbiol. online first [PubMed][PDF]
2008
Cadel-Six,S., Dauga,C., Castets,A.M., Rippka,R., Tandeau de Marsac,N., and Welker,M. (2008) Halogenase genes in two non-ribosomal peptide synthetase gene clusters of Microcystis (Cyanobacteria): sporadic distribution and evolution. Mol.Biol.Evol. 25: 2031-2041. [PubMed] [PDF]
Degenkolb,T., Dieckmann,R., Nielsen,K.F., Grafenhan,T., Theis,C., Zafari,D., Chaverri,P., Ismaiel,A. et al. (2008) The Trichoderma brevicompactum clade: a separate lineage with new species, new peptaibiotics, and mycotoxins. Mycological Progress 7: 177-219. [PDF]
Erhard,M., Hipler,U.C., Burmester,A., Brakhage,A.A., and Wöstemeyer,J. (2008) Identification of dermatophyte species causing onychomycosis and tinea pedis by MALDI-TOF mass spectrometry. Exp.Dermatol. 17: 365-371. [PubMed][PDF]
Graeber,I., Kaesler,I., Borchert,M.S., Dieckmann,R., Pape,T., Lurz,R., Nielsen,P., von Dohren,H. et al. (2008) Spongiibacter marinus gen. nov., sp nov., a halophilic marine bacterium isolated from the boreal sponge Haliclona sp 1. Int. J. Syst. Evol. Microbiol. 58: 585-590. [PubMed][PDF]
Kaesler,I., Graeber,I., Borchert,M.S., Pape,T., Dieckmann,R., von Doehren,H., Nielsen,P., Lurz,R. et al. (2008) Spongiispira norvegica gen. nov., sp nov., a marine bacterium isolated from the boreal sponge Isops phlegraei. Int. J. Syst. Evol. Microbiol. 58: 1815-1820. [PubMed][PDF]
Lasch,P., Nattermann,H., Erhard,M., Stämmler,M., Grunow,R., Bannert,N., Appel,B., and Naumann,D. (2008) A MALDI-ToF mass spectrometry compatible inactivation method for highly pathogenic microbial cells and spores. Anal.Chem. 80: 2026-2034. [PubMed][PDF]
Seyfarth,F., Ziemer,M., Kaatz,M., Sayer,H., Burmester,A., Erhard,M., Welker,M., Schliemann,S. et al. (2008) Case report: The use of ITS DNA sequence analysis and MALDI-TOF mass spectrometry in diagnosing an infection with Fusarium proliferatum. Exp.Dermatol. 17: 965-971. [PubMed][PDF]
Vanlaere,E., Sergeant,K., Dawyndt,P., Kallow,W., Erhard,M., Sutton,H., Dare,D., Samyn,B. et al. (2008) Matrix assisted laser desorption ionization-time of flight mass spectrometry of intact cells allows rapid identification of Burkholderia cepacia complex species. J.Microb.Meth. 75: 279-286. [PubMed][PDF]
Welker,M. (2008) Cyanobacterial hepatotoxins: microcystins, nodularins, and cylindrospermopsins. Botana, L. M. Seafood and freshwater toxins: pharmacology, physiology and detection, 2nd edition. 825-844. London, Taylor & Francis Group.
2007
Ishida,K., Christiansen,G., Yoshida,W.Y., Welker,M., Bonjoch,J., Hertweck,C., Börner,T., Hemscheidt,T.K., and Dittmann,E. (2007) Biosynthetic pathway and structure analysis of aeruginoside 126A and B, cyanobacterialpeptides bearing an unusual 2-carboxy-6-hydroxyoctaindole moiety. Chem.Biol. 14: 565-576. [PubMed][PDF]
Neuhof,T., Dieckmann,R., Druzhinina,I.S., Kubicek,C.P., and von Döhren,H. (2007) Intact-cell MALDI-TOF mass spectrometry analysis of peptaibol formation by the genus Trichoderma/Hypocrea: can molecular phylogeny of species predict peptaibol structures? Microbiology 153: 3417-3437. [PubMed][PDF]
Neuhof,T., Dieckmann,R., Druzhinina,I.S., Kubicek,C.P., Nakari-Setälä,T., Penttilä,M., and von Döhren,H. (2007) Direct identification of hydrophobins and their processing in Trichoderma using intact-cell MALDI-TOF MS. FEBS J. 274: 841-852. [PubMed][PDF]
Welker,M., Erhard,M. (2007) Consistency between chemotyping of single filaments of Planktothrix rubescens (cyanobacteria) by MALDI-TOF and the peptide patterns of strains determined by HPLC-MS. J.Mass Spectrom. 42: 1062-1068. [PubMed][PDF]
Welker,M., Sejnohova,L., von Döhren,H., Nemethova,D., Jarkovsky,J., and Marsalek,B. (2007) Seasonal shifts in chemotype composition of Microcystis sp. communities in the pelagial and the sediment of a shallow reservoir. Limnol.Oceanogr. 52: 609-619.
2006
Agrawal,M.K., Ghosh,S., Bagchi,D., Weckesser,J., Erhard,M., and Bagchi,S.N. (2006) Occurrence of microcystin-containing toxic water blooms in central India. J.Microbiol.Biotechnol. 16: 212-218.
Boaru,D.A., Dragos,N., Welker,M., Bauer,A., Nicoara,A., and Schirmer,K. (2006) Toxic potential of microcystin-containing cyanobacterial extracts from three Romanian freshwaters. Toxicon 47: 925-932. [PubMed][PDF]
Czarnecki,O., Lippert,I., Henning,M., and Welker,M. (2006) Identification of peptide metabolites of Microcystis (Cyanobacteria) that inhibit trypsin-like activity in planktonic herbivorous Daphnia (Cladocera). Environ.Microbiol. 8: 77-87. [PubMed][PDF]
Welker,M., Marsalek,B., Sejnohova,L., and von Döhren,H. (2006) Detection and identification of oligopeptides in Microcystis (cyanobacteria) colonies: toward an understanding of metabolic diversity. Peptides 27: 2090-2103. [PubMed][PDF]
Welker,M., von Döhren,H. (2006) Cyanobacterial peptides - Nature's own combinatorial biosynthesis. FEMS Microbiol.Rev. 30: 530-563. [PubMed][PDF]
2005
Dieckmann,R., Graeber,I., Kaesler,I., Szewzyk,U., and von Döhren,H. (2005) Rapid screening and dereplication of bacterial isolates from marine sponges of the Sula Ridge by Intact-Cell-MALDI-TOF mass spectrometry (ICM-MS). Appl.Microbiol.Biotechnol. 67: 539-548. [PubMed][PDF]
Kroppenstedt,R.M., Mayilraj,S., Wink,J.M., Kallow,W., Schumann,P., Secondini,C., and Stackebrandt,E. (2005) Eight new species of the genus Micromonospora, Micromonospora citrea sp. nov., Micromonospora echinaurantiaca sp. nov., Micromonospora echinofusca sp. nov., Micromonospora fulviviridis sp. nov., Micromonospora inyonensis sp. nov., Micromonospora peucetia sp. nov., Micromonospora sagamiensis sp. nov., and Micromonospora viridifasciens sp. nov. Syst.Appl.Microbiol. 28: 328-339. [PubMed]
Lopez-Legentil,S., Dieckmann,R., Bontemps-Subelos,N., Turon,X., and Banaigs,B. (2005) Qualitative variation of alkaloids in color morphs of Cystodytes (Ascidiacea). Biochem.Syst.Evol. 33: 1107-1119. [PDF]
Neuhof,T., Schmieder,P., Preussel,K., Dieckmann,R., Pham,H., Bartl,F., and von Döhren,H. (2005) Hassallidin, a glycosylated lipopeptide with antifungal activity from the cyanobacterium Hassallia sp. J.Nat.Prod. 68: 695-700. [PubMed][PDF]
Schmidt,O., Kallow,W. (2005) Differentiation of indoor wood decay fungi with MALDI-TOF mass spectrometry. Holzforschung 59: 374-377. [PDF]
Stackebrandt,E., Päuker,O., and Erhard,M. (2005) Grouping Myxococci (Corallococcus) strains by matrix-assisted laser desorption ionization time-of-flight (MALDI TOF) mass spectrometry: comparison with gene sequence phylogenies. Curr.Microbiol. 50: 71-77. [PubMed][PDF]
2004
Etchegaray,A., Rabello,E., Dieckmann,R., Moon,D.H., Fiore,M.F., von Döhren,H., Tsai,S.M., and Neilan,B.A. (2004) Algicide production by the filamentous cyanobacterium Fischerella sp CENA 19. J.Appl.Phycol. 16: 237-243. [PubMed]
Via-Ordorika,L., Fastner,J., Kurmayer,R., Hisbergues,M., Dittmann,E., Komárek,J., Erhard,M., and Chorus,I. (2004) Distribution of microcystin-producing and non-microcystin-producing Microcystis sp in European freshwater bodies: Detection of microcystins and microcystin genes in individual colonies. Syst.Appl.Microbiol. 27: 592-602. [PubMed]
Welker,M., Brunke,M., Preussel,K., Lippert,I., and von Döhren,H. (2004) Diversity and distribution of Microcystis (Cyanobacteria) oligopeptide chemotypes from natural communities studied by single colony mass spectrometry. Microbiology SGM 150: 1785-1796. [PubMed] [PDF]
Welker,M., Christiansen,G., and von Döhren,H. (2004) Diversity of coexisting Planktothrix (Cyanobacteria) chemotypes deduced by mass spectral analysis of microcystins and other oligopeptides. Arch.Microbiol. 182: 288-298. [PubMed][PDF]
2003
Christiansen,G., Fastner,J., Erhard,M., Börner,T., and Dittmann,E. (2003) Microcystin biosynthesis in Planktothrix: Genes, evolution, and manipulation. J.Bacteriol. 185: 564-572. [PubMed][PDF]
Matern,U., Oberer,L., Erhard,M., Herdman,M., and Weckesser,J. (2003) Hofmannolin, a new cyanopeptolin from Scytonema hofmanni PCC7110. Phytochemistry 64: 1061-1067. [PubMed][PDF]
Rohrlack,T., Christoffersen,K., Hansen,P.E., Zhang,W., Czarnecki,O., Henning,M., Fastner,J., Erhard,M. et al. (2003) Isolation, characterization, and quantitative analysis of microviridin J, a new Microcystis metabolite toxic to Daphnia. J.Chem.Ecol. 29: 1757-1770. [PubMed][PDF]
2002 and earlier
Welker,M., Fastner,J., Erhard,M., and von Döhren,H. (2002) Application of MALDI-TOF MS in cyanotoxin research. Environ.Toxicol. 17: 367-374. [PubMed]
Dittmann,E., Erhard,M., Kaebernick,M., Scheler,C., Neilan,B.A., von Döhren,H., and Börner,T. (2001) Altered expression of two light-dependent genes in a microcystin-lacking mutant of Microcystis aeruginosa PCC 7806. Microbiology SGM 147: 3113-3119. [PubMed] [PDF]
Fastner,J., Erhard,M., and von Döhren,H. (2001) Determination of oligopeptide diversity within a natural population of Microcystis spp. (Cyanobacteria) by typing single colonies by matrix-assisted laser desorption ionization-time of flight mass spectrometry. Appl.Environ.Microbiol. 67: 5069-5076. [PubMed][PDF]
Tillett,D., Dittmann,E., Erhard,M., von Döhren,H., Börner,T., and Neilan,B.A. (2000) Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-poliketide synthetase system. Chem.Biol. 7: 753-764. [PubMed][PDF]
Erhard,M., von Döhren,H., and Jungblut,P. (1999) Rapid identification of the new anabaenopeptin G from Planktothrix agardhii HUB 011 using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Comm.Mass Spectrom. 13: 337-343. [PubMed][PDF]
Dittmann,E., Neilan,B.A., Erhard,M., von Döhren,H., and Börner,T. (1997) Insertional mutagenesis of a peptide synthetase gene that is responsible for hepatotoxin production in the cyanobacterium Microcystis aeruginosa PCC 7806. Mol.Microbiol. 26: 779-787. [PubMed]
Erhard,M., von Döhren,H., and Jungblut,P. (1997) Rapid typing and elucidation of new secondary metabolites of intact cyanobacteria using MALDI-TOF mass spectrometry. Nat.Biotechnol. 15: 906-909. [PubMed][PDF]